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Awarded Trial: 02-STN-009
Grant ID
02-STN-009
Illness
Schizophrenia
Primary Drug/Intervention
Tamoxifen
Primary Dosage
up to 80 mg per day
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Lieberman
Sample Size
26
Duration of Study Period for Each Subject
4 weeks
Outcome Measurements
PANSS, CGI, CRRS, YMRS
Results
Twenty six subjects with treatment-refractory schizophrenia or schizoaffective disorder were randomized to receive tamoxifen (up to 80 mg per day) or placebo for 4 weeks. Patients continued to take standard antipsychotics. There was no significant difference on PANSS, CGI, CRRS, YMRS or side effect rating scales between placebo or tamoxifen.
Publication
N/A
Link
N/A
PI Name
Jeffrey Lieberman
Degree
MD
Center
N/A
Institution
University of North Carolina
Address
CB # 7160, 7025 Neurosciences Hospital
City or Town
Chapel Hill
State or Province
NC
Zip or Postal Code
27599
Country
USA
Email Address
jlieberman@unc.edu