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Awarded Trial: 02I-008

Grant ID

02I-008

Illness

Bipolar Depression

Primary Drug/Intervention

Danshen

Primary Dosage

200 mg t.i.d.

Secondary Drug Intervention

N/A

Secondary Dosage

N/A

Other Drug/Intervention

N/A

Other Dosage

N/A

Status

Completed

Investigator

Wang

Sample Size

140

Duration of Study Period for Each Subject

12 weeks

Outcome Measurements

HDRS, CGI-S, TESS

Results

One hundred and forty-two (142) elderly individuals with bipolar depression were randomized to adjunct Danshen or placebo for 12 weeks. There was no difference in clinical efficacy. Those on Danshen had fewer non-perseverative errors on the Wisconsin Card Sort (p<0.05), but this was not corrected for multiple measures.

Publication

N/A

Link

N/A

PI Name

Liwei Wang

Degree

MD

Center

N/A

Institution

Huashan Hospital, Fudan University Medical School

Address

12 Central Urumoi Road, Dept. of Psychiatry

City or Town

Shanghai

State or Province

N/A

Zip or Postal Code

200040

Country

China

Email Address

liweixu@online.sh.cn