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Awarded Trial: 05T-680
Grant ID
05T-680
Illness
Bipolar Disorder
Primary Drug/Intervention
Insulin
Primary Dosage
40 IU q.i.d.
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
McIntyre
Sample Size
60
Duration of Study Period for Each Subject
8 weeks
Outcome Measurements
HRSD, YMRS
Results
The objective was to assess the effects of intranasal insulin on cognitive function in euthymic BP patients. Sixty BP patients were randomized to intranasal insulin or placebo for 8 wks. Cognitive testing showed improvement in both groups but no significant difference between them.
Publication
Posthoc analysis: Yim CY, Soczynska JK, Kennedy SH, Woldeyohannes HO, Brietzke E, Intyre RS. The effect of overweight/obesity on cognitive function in euthymic individuals with bipolar disorders. Eur Psychiatry 2011 May 11.
Link
http://www.ncbi.nlm.nih.gov/pubmed/21570263
PI Name
Roger McIntyre
Degree
MD
Center
N/A
Institution
University of Toronto, University Health Network
Address
399 Bathurst Street, MP 9-325
City or Town
Toronto
State or Province
Ontario
Zip or Postal Code
M5T 2S8
Country
Canada
Email Address
roger.mcintyre@uhn.on.ca