Back to Awarded Treatment Trials
Awarded Trial: 06TGF-981
Grant ID
06TGF-981
Illness
Bipolar Disorder
Primary Drug/Intervention
Valacyclovir
Primary Dosage
1000 mg twice daily
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Payne
Sample Size
60
Duration of Study Period for Each Subject
16 weeks
Outcome Measurements
PANSS, CGI, YMRS, RBANS, MADRS
Results
Payne et al. randomized 60 BPI and II, average age 45, all HSV-1 positive, to valacylcovir 2 gm./d. for 16 weeks. On RBANS 10/19 (53%) on valacyclovir and 3/22 (14%) controls improved significantly on cognition but not on positive or negative symptoms. Data analysis is continuing.
Publication
Being submitted.
Link
N/A
PI Name
Jennifer Payne
Degree
MD
Center
Department of Psychiatry
Institution
The Johns Hopkins University
Address
600 N. Wolfe Street
City or Town
Baltimore
State or Province
MD
Zip or Postal Code
21287
Country
USA
Email Address
jpayne5@jhmi.edu