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Awarded Trial: 07TGS-1025
Grant ID
07TGS-1025
Illness
Schizophrenia
Primary Drug/Intervention
Allopurinol
Primary Dosage
300 mg/bid
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Dickerson
Sample Size
34
Duration of Study Period for Each Subject
70 days
Outcome Measurements
PANSS, RBANS
Results
Fifty-two patients with schizophrenia received 600 mg of allopurinol or placebo for 8 weeks in a double-blind trial. Those receiving allopurinol had a greater improvement in their PANSS score; 4 of 27 had more than a 20 percent improvement, while 0 of the 24 controls had this much improvement. Also, 14 of the 27 on allopurionol reported subjective improvement compared to 4 of 25 on the placebo.
Publication
N/A
Link
N/A
PI Name
Faith Dickerson
Degree
PhD
Center
N/A
Institution
Sheppard Pratt
Address
6501 North Charles Street
City or Town
Baltimore
State or Province
MD
Zip or Postal Code
21204
Country
USA
Email Address
fdickerson@sheppardpratt.org