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Awarded Trial: 07TGS-1054

Grant ID

07TGS-1054

Illness

Bipolar Disorder

Primary Drug/Intervention

Naltrexone

Primary Dosage

50 mg/day

Secondary Drug Intervention

N/A

Secondary Dosage

N/A

Other Drug/Intervention

N/A

Other Dosage

N/A

Status

Completed

Investigator

Murphy

Sample Size

30

Duration of Study Period for Each Subject

90 days

Outcome Measurements

CGI, HAM-D, YMRS, MADRS

Results

This was a pilot study of adjunct naltrexone to improve bipolar depression. Thirty-four (34) patients were randomized to naltrexone 50 mg/d for 12 weeks in a double-blind design. No differences were observed in mood improvement between the two groups.

Publication

N/A

Link

N/A

PI Name

Beth Murphy

Degree

MD

Center

McLean Hospital

Institution

Frazier Research Institute

Address

115 Mill Street

City or Town

Belmont

State or Province

MA

Zip or Postal Code

2474

Country

USA

Email Address

murphyb@mcleanpo.mclean.org