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Awarded Trial: 07TGS-1054
Grant ID
07TGS-1054
Illness
Bipolar Disorder
Primary Drug/Intervention
Naltrexone
Primary Dosage
50 mg/day
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Murphy
Sample Size
30
Duration of Study Period for Each Subject
90 days
Outcome Measurements
CGI, HAM-D, YMRS, MADRS
Results
This was a pilot study of adjunct naltrexone to improve bipolar depression. Thirty-four (34) patients were randomized to naltrexone 50 mg/d for 12 weeks in a double-blind design. No differences were observed in mood improvement between the two groups.
Publication
N/A
Link
N/A
PI Name
Beth Murphy
Degree
MD
Center
McLean Hospital
Institution
Frazier Research Institute
Address
115 Mill Street
City or Town
Belmont
State or Province
MA
Zip or Postal Code
2474
Country
USA
Email Address
murphyb@mcleanpo.mclean.org