Back to Awarded Treatment Trials
Awarded Trial: 08TGF-1189
Grant ID
08TGF-1189
Illness
Schizophrenia
Primary Drug/Intervention
Pregnenolone
Primary Dosage
50 mg/day
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Ritsner
Sample Size
60
Duration of Study Period for Each Subject
56 days
Outcome Measurements
PANSS, CGI, SANS, The Calgary Depression Scale, Barnes Akathisia Scale, Global Assessment of Functioning, Quality of Life Scale, The CANTAB battery
Results
Gave pregnenolone 50 mg or placebo to 60 recent-onset schiz or schizoaffective patients for 8 wks. Reported significant improvement in negative symptoms (PANSS), quality of life (QLS scale), and global assessment of functioning (GAF).
Publication
N/A
Link
N/A
PI Name
Michael Ritsner
Degree
MD
Center
Sha'ar Menashe Mental Health Center
Institution
The Rappaport Faculty of Medicine, Technion Institute
Address
Sha'ar Menashe MHC, Mobile Post Hefer 38814
City or Town
Hadera
State or Province
N/A
Zip or Postal Code
38814
Country
Israel
Email Address
ritsner@sm.health.gov.il