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Awarded Trial: 14T-009
Grant ID
14T-009
Illness
Schizophrenia
Primary Drug/Intervention
Sulforaphane
Primary Dosage
2 tablets
Secondary Drug Intervention
Minocycline
Secondary Dosage
200 mg/day
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Jin
Sample Size
300
Duration of Study Period for Each Subject
336 days
Outcome Measurements
To examine the effects of sulforaphane and minocycline in prodromic schizophrenia patients on: 1) Cognitive improvement (measured by Chinese version MATRICS and expended cognitive battery) based on Global Deficit Score (GDS) 2) Reduction of clinical symptoms (SOPS) and conversion to psychosis 3) Improvement of inflammatory biomarkers (reduce IL-1B and TNF-a) 4) Social Functioning and mood (GAF and MADRD) 5) Safety
Results
N/A
Publication
N/A
Link
N/A
PI Name
Hua Jin
Degree
MD
Center
N/A
Institution
University of California San Diego
Address
3350 La Jolla Village Drive, Mail Code 116A-1
City or Town
San Diego
State or Province
CA
Zip or Postal Code
92161
Country
USA
Email Address
hjin@ucsd.edu