Back to Awarded Treatment Trials
Awarded Trial: 04T-624
Grant ID
04T-624
Illness
Bipolar Disorder
Primary Drug/Intervention
Folate, B6, B12
Primary Dosage
10 mg/day
Secondary Drug Intervention
B6
Secondary Dosage
80 mg/day
Other Drug/Intervention
B12
Other Dosage
2 mg/day
Status
Completed
Investigator
Dittmann
Sample Size
90
Duration of Study Period for Each Subject
2 years
Outcome Measurements
Cognitive battery, CGI-BP, HAM-D, YMRS
Results
In an attempt to improve cognitive function in patients with BP I or II, randomized 47 patients with an elevated homocycsteine level to folate 10 mg/d plus vitamin B-12, or placebo. On measures of cognitive function (RBANS, Trail Making Test), there was no difference between the groups among the 41 patients who completed the study.
Publication
Being submitted for publication.
Link
N/A
PI Name
Sandra Dittmann
Degree
PhD
Center
University of Munich
Institution
Ludwig-Maximilians Universitaet
Address
Nussbaumstr. 7
City or Town
Munich
State or Province
N/A
Zip or Postal Code
80336
Country
Germany
Email Address
sandra.dittmann@med.uni-muenchen.de