Grant ID

97-RC-299-13

Illness

Bipolar Disorder

Primary Drug/Intervention

Taurine

Primary Dosage

1-2 g/day

Secondary Drug Intervention

N/A

Secondary Dosage

N/A

Other Drug/Intervention

N/A

Other Dosage

N/A

Status

Completed

Investigator

Cohen

Sample Size

30

Duration of Study Period for Each Subject

3 months

Outcome Measurements

YMRS, CGI, GAF

Results

Only 16 patients out of the 30 enrolled completed all 12 weeks of the study. The taurine group had less depression than the placebo group, but the difference was not significant. Their original study showed a reduction in manic symptoms on taurine, but this study did not replicate that finding.

Publication

N/A

Link

N/A

PI Name

Bruce Cohen

Degree

MD

Center

McLean Hospital

Institution

N/A

Address

City or Town

Belmont

State or Province

MA

Zip or Postal Code

N/A

Country

USA

Email Address

cohenb@mclean.harvard.edu