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Awarded Trial: 07TGS-1073
Grant ID
07TGS-1073
Illness
Bipolar Depression
Primary Drug/Intervention
S-adenosyl-methionine (SAMe)
Primary Dosage
200 mg/d at start of study/up to 1600 mg/d
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Murphy
Sample Size
10
Duration of Study Period for Each Subject
63 days
Outcome Measurements
CGI, YMRS, MADRS, GAF
Results
Twenty (20) subjects with BP were randomized to SAMe or placebos. There were no clinical or statistical differences between the groups on the HAM-D, MADRS, or YMRS> The dose of SAMe used was relatively low.
Publication
N/A
Link
N/A
PI Name
Beth Murphy
Degree
MD
Center
McLean Hospital
Institution
Frazier Research Institute
Address
115 Mill Street
City or Town
Belmont
State or Province
MA
Zip or Postal Code
2478
Country
USA
Email Address
murphyb@mcleanpo.mclean.org